11 Nov 1620: Mayflower Compact signed The male passengers of the Mayflower signed a compact establishing a form of self-government for the Plymouth Colony.
21 Dec 1620: Pilgrims arrive at Plymouth The Pilgrims aboard the Mayflower land at what is now Plymouth, Massachusetts, founding the first permanent English settlement in New England.
2
1622
20 Mar 1622: Jamestown Massacre Native American tribes led by Chief Opechancanough attacked the English settlement of Jamestown, Virginia, killing nearly 350 colonists.
3
1629
4 Oct 1629: Massachusetts Bay Colony chartered King Charles I granted a royal charter to the Massachusetts Bay Company, leading to a large Puritan migration to the New World.
4
1630
1 Sep 1630: Founding of Boston Puritan colonists led by John Winthrop founded the city of Boston, which became the capital of the Massachusetts Bay Colony.
5
1636
18 Sep 1636: Harvard College founded The General Court of Massachusetts Bay Colony established Harvard College, the first institution of higher learning in the United States.
6
1639
14 Jan 1639: Fundamental Orders of Connecticut The settlements of Windsor, Hartford, and Wethersfield adopted the "Fundamental Orders," considered to be the first written constitution in America.
7
1643
25 Sep 1643: New England Confederation formed The colonies of Massachusetts Bay, Plymouth, Connecticut, and New Haven formed a military alliance for mutual defense against Native Americans.
8
1652
30 May 1652: Rhode Island outlawed slavery Rhode Island passed a law prohibiting slavery, though it was largely ignored and later repealed.
9
1663
24 Mar 1663: Carolina Charter granted King Charles II granted a charter to eight proprietors to establish the Carolina colony.
10
1664
2 Sep 1664: English seize New Netherland The English fleet seized the Dutch colony of New Netherland without a fight, renaming it New York.